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. 2022 Jan 20;12:758829. doi: 10.3389/fimmu.2021.758829

Figure 2.

Figure 2

SPRR3 knockdown alleviates house dust mite (HDM)-induced airway inflammation and mucus secretion in mice. (A) Immunohistochemistry staining of the lung to assess the expression of SPRR3 (original magnification, ×200). (B) SPRR3 protein levels in mouse lungs determined by Western blotting. (C) Representative lung sections stained with H&E (original magnification, ×200) and histopathological scores of airway inflammations. (D) Representative lung sections stained with periodic acid-Schiff (PAS) (original magnification, ×200) and histopathological scores of airway mucus secretion. Values represent mean ± SEM, n = 4–6 for each group. ** p < 0.01, *** p < 0.001.