Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 20;12:758829. doi: 10.3389/fimmu.2021.758829

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zhu, Cai, Ye, Mo, Zhu, Zeng, Song, Yang, Gao, Wang and Jin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

SPRR3 contributes to the upregulation of alarmins IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) after exposure to allergens in vitro. (A) mRNA expressions of IL-25, IL-33, TSLP, and SPRR3 in BEAS-2B cells at different times after exposure to house dust mite (HDM) (40 μg/ml). (B) mRNA expressions of IL-25, IL-33, TSLP, and SPRR3 in BEAS-2B cells exposed to different concentrations of HDM. (C) mRNA expressions of IL-25, IL-33, TSLP, and SPRR3 in BEAS-2B cells after transfection with SPRR3 siRNA or negative control siRNA prior to HDM exposure. Values represent mean ± SEM, n = 3 independent experiments. ^** p < 0.01, ^*** p < 0.001. ns, no significant difference.