Table 3.

The prognostic value of COUNT score for OS and RFS in pancreatic cancer and subgroup analysis.

Variables	No. of studies	No. of patients	HR (95% CI)	p	Heterogeneity		Effects model
					I2 (%) Ph
Overall survival
Total	7	2,294	1.56 (1.13–2.16)	0.007	89.0	<0.001	Random
Country
Japan	4	1,312	1.39 (1.15–1.69)	0.001	37.2	0.189	Fixed
China	3	982	1.87 (1.01–3.47)	0.048	95.9	<0.001	Random
Sample size
<330	3	685	1.74 (0.75–4.02)	0.198	92.2	<0.001	Random
≥330	4	1,609	1.31 (1.08–1.60)	0.007	54.2	0.088	Random
Treatment
Surgery	5	1,915	1.67 (1.15–2.41)	0.007	92.2	<0.001	Random
Surgery + chemotherapy/chemotherapy	2	379	1.17 (0.47–2.89)	0.731	67.8	0.078	Random
Cut-off value
≥2	1	382	1.15 (1.05–1.25)	0.002	–	–	–
≥3	4	1,261	1.61 (0.89–2.91)	0.112	90.8	<0.001	Random
≥4	2	651	1.67 (1.26–2.20)	<0.001	0	0.842	Fixed
Survival analysis
MVA	6	1,988	1.56 (1.04–2.34)	0.030	90.5	<0.001	Random
UVA	1	306	1.52 (1.18–1.94)	0.001	–	–	–
Recurrence-free survival
Total	5	1,606	1.47 (0.97–2.23)	0.072	85.6	<0.001	Random
Country
Japan	4	1,312	1.23 (0.95–1.59)	0.121	50.7	0.107	Random
China	1	294	2.93 (2.10–4.09)	<0.001	–	–	–
Sample size
<330	3	673	1.83 (1.03–3.25)	0.039	78.6	0.009	Random
≥330	2	933	1.11 (0.92–1.35)	0.267	0	0.971	Fixed
Treatment
Surgery	3	1,227	1.53 (0.85–2.73)	0.155	91.8	<0.001	Random
Surgery + chemotherapy/chemotherapy	2	379	1.37 (0.65–2.85)	0.406	67.9	0.078	Random
Cutoff value
≥3	3	955	1.47 (0.69–3.13)	0.318	90.7	<0.001	Random
≥4	2	651	1.41 (0.85–2.34)	0.187	78.3	0.032	Random

COUNT, controlling nutritional status; OS, overall survival; RFS, recurrence-free survival; MVA, multivariate analysis; UVA, univariate analysis.