Table 2.

Hazard ratios (95% CIs) for hypertension associated with aircraft noise in NHS, NHS II, and meta-analysis of both cohorts in separate models.

DNL category (in db(A))		Cases	Person Years	Basic Model^a HR (95% CI)	Parsimonious Model^b HR (95% CI)	Full Model^c HR (95% CI)
NHS
	≥45	2,452	48,862	1.05 (1.01, 1.10)	1.05 (1.01, 1.10)	1.05 (1.00, 1.09)
	<45	30,738	662,567	Ref.	Ref.	Ref.

	≥55	318	6,103	1.09 (0.97, 1.21)	1.07 (0.96, 1.20)	1.05 (0.94, 1.17)
	<55	32,872	705,325	Ref.	Ref.	Ref.
NHS II
	≥45	2,167	96,894	1.00 (0.95, 1.04)	1.02 (0.97, 1.07)	1.01 (0.96, 1.05)
	<45	26,089	1,170,950	Ref.	Ref.	Ref.

	≥55	314	12,758	1.10 (0.99, 1.23)	1.12 (1.00, 1.25)	1.08 (0.97, 1.21)
	<55	27,942	1,255,087	Ref.	Ref.	Ref.
Meta-analysis
	≥45	4,619	145,756	1.03 (0.97, 1.08)	1.04 (1.00, 1.07)	1.03 (0.99, 1.07)
	<45	56,827	1,833,517	Ref.	Ref.	Ref.

	≥55	632	18,861	1.09 (1.01, 1.18)	1.10 (1.01, 1.19)	1.07 (0.98, 1.15)
	<55	60,814	1,960,412	Ref.	Ref.	Ref.

Abbreviations: BMI, Body Mass Index; DASH, Dietary Approaches to Stop Hypertension; dB(A), A-Weighted Decibels; DNL, Day-Night Average Sound Level; HR, Hazard Ratio; NSAID, Non-Steroidal Analgesic Intake Drug; NHS, Nurses’ Health Study; NHS II, Nurses’ Health Study II; MET, Metabolic Equivalent; nSES, Neighborhood Level Socio-Economic Status.

Adjusted for age and calendar year.

Adjusted for age, calendar year, race, physical activity, smoking status, alcohol use, DASH, spouse’s education attainment, nSES (Census tract home value and household income), and region of residence.