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Ras mutations in human cancer. The parentheses indicate the predominant mutations.
| Ras isoform | Frequency of mutations | G12 mutation | G13 mutation | Q61 mutation | Others |
|---|---|---|---|---|---|
| KRas | 85% | 83% (G12D 41%) | 14% (G13D 89%) | 2% (Q61H 58%) | 2% |
| NRas | 11% | 23% (G12D 52%) | 12% (G13D 50%) | 63% (Q61R 47%) | 3% |
| HRas | 4% | 33% (G12V 57%) | 27% (G13R 85%) | 37% (Q61R 43%) | 3% |
