Table 3.

Fine-mapping posterior probabilities of k causal variants at novel primary GWAS and independent secondary signal loci

Trait	GWAS index variant	Locus	Posterior probability (no. of causal variants is k)
			k=1	k=2	k=3	k=4	k=5
Primary GWAS analysis loci
Fasting glucose	rs571025325	LRRC37A5P	0.62	0.38	4.74×10−7	0	0
Fasting insulin	rs9472142	VEGFA	0.37	0.48	0.15	0.01	0
Fasting insulin	rs35131928	CASC8/CASC21	0.72	0.28	0.0002	0	0
Fasting insulin	rs10887773	PTEN	0.78	0.22	0	0	0
Conditional analysis loci
Fasting insulin	rs330941	PPP1R3B	0.05	0.77	0.19	0	0
Fasting glucose	rs55908146	GCK/MYL7	0	0.04	0.37	0.54	0.06