TABLE 1.
Delivery, maternal and neonatal outcome measurements of pregnant mice
| Outcome measures | Vehicle | Progesterone | Promegestone |
|---|---|---|---|
| Term birth (number of dams) | 8/8 | 6/6 | 1/8 |
| Postterm birth (number of dams) | 0 | 0 | 7/8 |
| Delayed parturition (%) | 0 | 0 | 87.5 |
| Pregnancy weight gain (GD 15-labor, g) | 14.8±2a | 14.7±3.67a | 13.83±5.24a |
| Litter size (n) | 12.67±3.2b | 14.31±2.5b | 12.88±4.42b |
| Neonatal/fetal weight (g) | 1.52±0.2c | 1.76±0.16c | 1.70±0.21c |
Data are presented as mean±standard deviation, unless otherwise indicated.
GD, gestational day; Promegestone, synthetic progestin.
a
Indicates that pregnancy weight gain is not significantly different between groups (P>.05);
b
Indicates that litter size is not significantly different between groups (P>.05);
c
Indicates that neonatal/fetal weight is not significantly different between groups (P>.05).
Shynlova et al. Promegestone delays preterm labor in mice. Am J Obstet Gynecol 2021.