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. 2021 Nov 9;126(3):456–463. doi: 10.1038/s41416-021-01601-9

Table 2.

Patients with double PIK3CA mutations detected in plasma.

Patient ID First mutation in plasma (AF %) Second mutation in plasma (AF %) First mutation in tissue (%MAF) Second mutation in tissue (%MAF) Δ time (months)
B211 E542K (12.76) H1047R (0.33) E542K (28.57) None detected 20.3
B235 E542K (1.34) H1047R (0.77) None detected None detected 22.6
B259 E542K (1.71) H1047R (4.42) E542K (13.52) None detected 60.3
B387 E545K (16.36) E542K (9.87) E545K (62.09) E542K (26.66) 17.6