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Multivariate analysis of progression-free survival in the validation cohort.
| Characteristic | HRa | 95% CIb | P-value |
|---|---|---|---|
| WHO Performance status | |||
| 0 | Ref | ||
| 1–2 | 1.43 | 0.98, 2.08 | 0.061 |
| ctDNA | |||
| ctDNA negative | Ref | ||
| ctDNA positive | 1.50 | 1.03, 2.18 | 0.034 |
| CA19.9_median | |||
| ≤1366 | Ref | ||
| >1366 | 1.36 | 0.96, 1.92 | 0.085 |
Bold values indicate statistical significance p < 0.05.
Analysis was performed after stratification on studies and centers.
aHR Hazard ratio.
bCI confidence interval.
