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. 2022 Feb 2;8:43. doi: 10.1038/s41420-021-00807-3

Fig. 6. The inhibition of 4-OI for ferroptosis was abolished in Nrf2-KO mice.

Fig. 6

AC Relative GSH, GSH/GSSG ratio and MDA levels in murine lung tissue (n = 6). D, E Western blots for GPX4, PTGS2, Nrf2, GCLM and SLC7A11 in murine lung tissue. FI Relative mRNA levels of GPX4, GCLM, SLC7A11 and HO-1 in murine lung tissue (n = 6). J Relative iron levels of murine lung tissue (n = 6). (Data are presented as Mean ± SD *p < 0.05, **p < 0.01, ***p < 0.001).