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. 2022 Feb 3;13:8. doi: 10.1007/s12672-022-00469-2

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — CENPO was highly expressed in CRC. A Based on the information of 51 normal and 635 tumor samples from CRC patients in The Cancer Genome Atlas (TCGA) database, the differential expression of CENPO was analyzed. B The quantitative analysis results of CENPO in clinical tissues of IHC. C The typical images of IHC staining showed a significantly high signal intensity of CENPO in tumor tissue. Magnification was 200 and 400