Fig. 3.

Knockdown of CENPO enhanced apoptosis in CRC cells. A Flow cytometry analysis based on Annexin V-APC and PI staining was utilized to detect the apoptotic for HCT116 and RKO cells. B The alterations of apoptotic signaling pathway were preliminarily explored in CENPO knock downed HCT116 cells through Human apoptosis antibody array analysis. The presented results were representative of experiments repeated at least three times. Data was represented as mean  ±  SD. *P  < 0.05, **P  < 0.01, ***P  < 0.001