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CENPO regulated proliferation and apoptosis in a p53-dependent manner. A, B Cell counting experiment and flow cytometry were performed to analyze cell proliferation and apoptosis of HCT116 and RKO cells co-transfected with TP53 shRNA and TC2N shRNA (shTP53 + shCENPO). The presented results were representative of experiments repeated at least three times. Data was represented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001
