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. 2022 Jan 19;126(3):430–439. doi: 10.1038/s41416-021-01648-8

Fig. 3. ctDNA measurements are prognostic.

Fig. 3

a Kaplan–Meier overall survival curves showing better overall survival (OS) in patients with ctDNA aVAF ≤0.2. b Patients achieving clearance of their ctDNA aVAF at any time point had better overall survival. c Addition of ctDNA aVAF and ctDNA delta aVAF improved the accuracy of the multivariate model for the prediction of overall survival. The baseline model included age, sex, and liver metastasis. d Kaplan–Meier overall survival curve showing a worse OS of patients having PIK3CA genomic alterations.