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a The mean ctDNA aVAF increased significantly in samples corresponding to PD events compared to scans showing non-PD events (PD events = 45, non-PD events = 82). b The number of total genomic alterations per sample showed a significant decrease in ctDNA samples corresponding to non-PD events compared to samples corresponding to PD events. c The ctDNA delta aVAF was significantly increased with PD events and decreased in non-PD events.
