Fig. 1.
The miR-146a-5p mimetic increased markers of senescence and inflammation in visceral adipose tissue of df/df mice. A Expression of miR-146a-5p in visceral adipose tissue from df/df mice after miR-146a mimetic transfection. B β-galactosidase activity, C p16Ink4a expression in visceral adipose tissue from df/df mice after 4 or 8 μg/g of miR-146a mimetic injections. D IL-6 expression in visceral adipose tissue from df/df mice after 4 and 8 μg/g miR-146a mimetic injections. Values are means ± S.E.M. *p < 0.05 versus df/df control and + p < 0.05 versus all groups