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. 2022 Feb 2;12:1763. doi: 10.1038/s41598-022-04868-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The projected areas of nerve stimulation when a hypothetical tumor is ablated by pulses of different shape and duration. This example uses data from Figs. 2F and 9B and assumes uniform dielectric properties of the tissue. The tumor is placed between two needle electrodes which pierce the tissue orthogonal to the plane shown in the figure. Pulse amplitude is set to produce the electric field sufficient to ablate the tumor (“Ablation Area”). The larger radii mark the projected distances at which the nerve stimulation is expected when the tumor is ablated by pulses of a specific shape and duration (legends). See Figs. 2, 9, and text for more details.