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. 2021 Nov 25;44(1):519–532. doi: 10.1007/s11357-021-00491-2

Fig. 2.

Fig. 2

Observational cohort studies of physical activity and risk of pneumonia included in the meta-analysis. The summary estimate presented was calculated using fixed effects models and was based on fully adjusted estimates; sizes of data markers are proportional to the inverse of the variance of the relative ratio; CI, confidence interval (bars); PA, physical activity; RR, relative risk. The level of adjustment was defined as ‘ + ’ minimally adjusted analysis, i.e. age and/or sex; ‘ +  + ’ as adjustment for established risk factors without inflammation, i.e. age and/or sex plus body mass index, socioeconomic status, alcohol consumption, smoking, and comorbidities