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. 2022 Jan 20;8:816802. doi: 10.3389/fmed.2021.816802

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Copyright © 2022 Ke, Chen, Yaling, Can, Jun and Chuan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Beta analysis of microbial diversity in sputum samples of COPD frequent exacerbators and COPD infrequent exacerbators. E represented COPD frequent exacerbators; I represented COPD infrequent exacerbators. COPD, chronic obstructive pulmonary disease.