Table 3.
Univariate regression and multivariate survival model of prognostic covariates in patients with LUAD.
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| T stage | 981 | ||||
| T1 | 279 | ||||
| T2 | 546 | 1.372 (1.064-1.769) | 0.015 | 0.945 (0.640-1.394) | 0.775 |
| T3&T4 | 156 | 2.438 (1.791-3.318) | <0.001 | 2.061 (1.184-3.585) | 0.011 |
| N stage | 964 | ||||
| N0 | 629 | ||||
| N1 | 218 | 1.558 (1.232-1.970) | <0.001 | 1.132 (0.778-1.647) | 0.516 |
| N2&N3 | 117 | 2.115 (1.593-2.808) | <0.001 | 2.159 (1.036-4.497) | 0.040 |
| M stage | 757 | ||||
| M0 | 728 | ||||
| M1 | 29 | 2.461 (1.560-3.883) | <0.001 | 2.135 (0.927-4.918) | 0.075 |
| hsa-miR-30a-5p | 984 | 0.917 (0.835-1.008) | 0.043 | 0.967 (0.836-1.118) | 0.647 |
| Pathologic stage | 973 | ||||
| Stage I&Stage II | 783 | ||||
| Stage III&Stage IV | 190 | 2.103 (1.683-2.628) | <0.001 | 0.758 (0.375-1.531) | 0.440 |
| Primary therapy outcome | 771 | ||||
| SD&CR | 664 | ||||
| PD&PR | 107 | 4.010 (3.049-5.273) | <0.001 | 5.218 (3.420-7.961) | <0.001 |
| Residual tumor | 739 | ||||
| R0 | 709 | ||||
| R2&R1 | 30 | 3.016 (1.863-4.882) | <0.001 | 1.654 (0.759-3.602) | 0.205 |
| Smoker | 959 | ||||
| No | 89 | ||||
| Yes | 870 | 0.920 (0.640-1.324) | 0.654 | ||
| Race | 808 | ||||
| White | 726 | ||||
| Black or African American | 82 | 1.004 (0.711-1.419) | 0.981 | ||