Table 2.
Comprehensive insight to the bioactive component's retention and bioavailability of nanocapsules.
| Nanomaterial | Nanomaterial structure | Average size (nm) | Synthesis of food nanomaterial | Oral administration | Interaction with human organ/cells | Biocompatibility assessment | References |
|---|---|---|---|---|---|---|---|
| Nanocapsule |
|
< 0.2 μm | Sodium alginate concentration is used to prepare nanoencapsulated quercetin | Nanoencapsulated bioactive compound quercetin | Prevent low gastric pH and during the digestion process optimize their release | Showed absent or low toxicity in vitro in different cell models and improved the bioavailability | (113) |
| Nanoliposomes |
|
10 nm | Prepared by scattering the lipids in media that is aqueous and by purifying and analyzing | Nanoencapsulated curcumin | Interact with intestine by bile salts without the dispersion owing to their extra small size | Enhanced nutrients' bioavailability, safety of food, and improved bioaccessibility | (114) |
| Starch nanoparticles |
|
322.7 nm | Obtained from lotus stem | Nanoencapsulated catechin | Provide controlled intestinal release | Availability of high bioactive compounds, prevent various diseases | (75) |
| Nanostructured lipid capsules |
|
50–300 nm | Formed by interaction with various polyphenols such as catechin | Nanoencapsulation of polyphenols | Enhanced oral bioavailability and interact with gastrointestinal tract to gain high stability | Provide physiological treatment of several organs by acting as dietary supplements | (115) |