Table 3.
Comparison of the number of prescribed medications and adverse events in the adherent and non-adherent patient groups.
| Adherent patients (n = 845) | Non-adherent patients (n = 217) | Statistic | p-value | Effect size | |
|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | ||||
| Cross-diagnostic group | |||||
| Antidepressants | 0.51 (0.65) | 0.43 (0.60) | U = 68267.50, z = –1.54 | 0.123 | r = –0.047 |
| Antipsychotics | 1.38 (0.98) | 1.25 (0.92) | U = 85064.50, z = –1.74 | 0.081 | r = –0.053 |
| Mood stabilizers | 0.46 (0.61) | 0.29 (0.48) | U = 78900.00, z = –3.73 | 0.000 | r = –0.114 |
| Tranquilizers | 0.21 (0.46) | 0.26 (0.50) | U = 86837.50, z = –1.76 | 0.079 | r = –0.054 |
| Other psychotherapeutics | 0.02 (0.18) | 0.01 (0.12) | U = 91538.00, z = –0.17 | 0.865 | r = –0.005 |
| Overall | 2.58 (1.30) | 2.24 (1.21) | U = 78411.50, z = –3.40 | 0.001 | r = –0.104 |
| Psychotic disorder group | |||||
| Antidepressants | 0.34 (0.55) | 0.29 (0.51) | U = 24386.00, z = –0.81 | 0.416 | r = –0.025 |
| Antipsychotics | 1.84 (0.88) | 1.56 (0.91) | U = 20854.50, z = –3.22 | 0.001 | r = –0.099 |
| Mood stabilizers | 0.15 (0.40) | 0.12 (0.32) | U = 24768.00, z = –0.67 | 0.506 | r = –0.020 |
| Tranquilizers | 0.27 (0.50) | 0.27 (0.50) | U = 25284.50, z = –0.06 | 0.954 | r = –0.001 |
| Other psychotherapeutics | 0.01 (0.09) | 0.02 (0.12) | U = 25149.00, z = –0.80 | 0.426 | r = –0.025 |
| Overall | 2.62 (0.09) | 2.26 (1.19) | U = 21324.00, z = –2.80 | 0.005 | r = –0.056 |
| Bipolar disorder group | |||||
| Antidepressants | 0.57 (0.67) | 0.53 (0.63) | U = 13711.50, z = –0.39 | 0.695 | r = –0.012 |
| Antipsychotics | 1.03 (0.90) | 0.92 (0.75) | U = 13390.50, z = –0.71 | 0.477 | r = –0.022 |
| Mood stabilizers | 0.83 (0.60) | 0.65 (0.56) | U = 12039.50, z = –2.27 | 0.023 | r = –0.070 |
| Tranquilizers | 0.16 (0.44) | 0.26 (0.53) | U = 12795.50, z = –2.01 | 0.044 | r = –0.062 |
| Other psychotherapeutics | 0.03 (0.17) | 0.01 (0.12) | U = 13947.00, z = –0.29 | 0.623 | r = –0.009 |
| Overall | 2.62 (1.30) | 2.38 (1.24) | U = 12725.00, z = –1.34 | 0.181 | r = –0.041 |
| Unipolar depression group | |||||
| Antidepressants | 1.16 (0.64) | 1.06 (0.68) | U = 454.50, z = –0.48 | 0.628 | r = –0.015 |
| Antipsychotics | 0.66 (0.65) | 0.25 (0.45) | U = 326.00, z = –2.28 | 0.023 | r = –0.070 |
| Mood stabilizers | 0.10 (0.30) | 0.06 (0.25) | U = 470.50, z = –0.44 | 0.659 | r = –0.014 |
| Tranquilizers | 0.10 (0.30) | 0.19 (0.00) | U = 444.50, z = –0.44 | 0.326 | r = –0.014 |
| Other psychotherapeutics | 0.02 (0.13) | 0 | U = 480.00, z = –0.51 | 0.448 | r = –0.016 |
| Overall | 2.03 (1.05) | 1.56 (1.09) | U = 375.00, z = –1.47 | 0.458 | r = –0.045 |
| Adverse events | |||||
| Yes | 404 (52.9) | 85 (39.8) | X2(1) = 8.39 | 0.004 | Φ = 0.089 |
Bold values indicate significance (p < 0.05).
r, Pearson correlation coefficient: <0.3, small effect size; 0.3–0.5, medium effect size; >0.5, large effect size.
ϕ, Phi coefficient: <0.25, small effect size; 0.25–0.66, medium effect size; >0.66, large effect size.