Fig. 1.

(a) High fat diet increases body weight in specific pathogen free (SPF) mice. Body weight gain was significant during the first 2 weeks of experimental feeding. ****p < 0.0001 and **p < 0.01 for high fat diet (HFD) relative to control chow diet (CD) and was maintained at 4 weeks; p < 0.05. SPF CD: n = 10; SPF HFD: n = 10. Fatty acid concentration in the (b) serum and from (c) livers of SPF mice after four weeks following high fat diet (HFD) relative to control chow diet (CD). Values are given as median +/- 95% CI for n = 10 per group.