Table 1.

Comparison of demographics for all active participants, participants that did not conceive and those that were lost to follow-up

	Total no active patients continuing in cohort	Those that did not conceive within the continuing cohort	P value
No	639	106
Age mean (range)	33.7 (18-46)	34.03 (22-47)	0.092
Ethnicity	White: 84% (436/519)	White 85.5% (65/76)
	Mixed: 2.1% (11)	Mixed: 2.6% (2)
	Asian: 8.9% (46)	Asian: 6.6% (5)
	Black: 3.3% (17)	Black: 3.9% (3)
	Other: 1.7% (9)	Other: 1.3% (1)
	Unknown (120)	Unknown (30)
Average no of previous live birth	0.6	0.15	0.36
Average no of previous miscarriages	3.5	3.6
BMI over 30	23.8% (n=126/530)	30% (n=26/87)	0.001
Smoking Y/N	Yes:41 (7.4%)	Yes: 12 (13.5%)	0.001
Alcohol Y/N	Yes: 278 (50%)	Yes: 51 (58%)	0.083
Units	5.54 (0.5–30)	5.03 (0.5–35)	<0.001
Folic acid	Yes: 292 (45.5%)	Yes: 35 (47.17%)	<0.001

BMI, body mass index.