Table 1.
Model inputs, varied by mRS score
| Probability and utility inputs | |||
| State | mRS probability (rangea) | Short term utilityb (rangea) | Long term utility [12–14] (rangea) |
| mRS 0 | 0.1654 (0.1489–0.1820)b | 0.85 (0.76–1.00) | 0.85 (0.80–1.00) |
| mRS 1 | 0.2964 (0.2668–0.3261)b | 0.78 (0.67–0.94) | 0.80 (0.75–0.90) |
| mRS 2 | 0.2551 (0.2296–0.2806)b | 0.67 (0.53–0.89) | 0.70 (0.53–0.75) |
| mRS 3 | 0.1379 (0.1241–0.1516)b | 0.30 (0.12–0.42) | 0.51 (0.45–0.65) |
| mRS 4 | 0.0276 (0.0248–0.0303)b | 0.11 (0.02–0.20) | 0.30 (0.25–0.55) |
| mRS 5 | 0.0310 (0.0279–0.0341)b | 0.03 (0.00–0.07) | 0.15 (0.00–0.32) |
| mRS 6 | 0.0866 (0.0779–0.0953) [9] | – | – |
| Short term annual costb, AUD | |||
| State | Medical (rangea) | Nonmedical (rangea) | Indirect (rangea) |
| mRS 0 | 15,464 (5685-26,522) | 570 (0–1140) | 14,733 (0–32,196) |
| mRS 1 | 21,901 (6106-39,353) | 2112 (0–4224) | 27,400 (0–50,593) |
| mRS 2 | 40,408 (14,837-51,458) | 5236 (140–6460) | 47,534 (0–87,389) |
| mRS 3 | 68,199 (44,273-68,953) | 30,821 (13,133-40,867) | 36,357 (0–87,389) |
| mRS 4 | 85,578 (71,406-103,792) | 58,569 (29,341-74,610) | 43,301 (0–91,988) |
| mRS 5 | 140,089 (71,464-161,818) | 82,999 (46,339-70,034) | 40,781 (0–87,389) |
| mRS 6 | 43,644 (3918-42,359) | 19,738 (0–2627) | 39,612 (0–82,789) |
| Long term annual cost, AUD | |||
| State | Medical [6, 15] (rangea) | Nonmedical [6, 15] (rangea) | Indirect [16] (rangea) |
| mRS 0 | 1400 (0–2800) | 576 (0–1152) | – |
| mRS 1 | 1400 (0–2800) | 576 (0–1152) | 2998 (0–5996) |
| mRS 2 | 1774 (0–3548) | 730 (0–1460) | 19,855 (0–39,710) |
| mRS 3 | 1774 (0–3548) | 730 (0–1460) | 27,875 (0–55,750) |
| mRS 4 | 13,715 (0–27,430) | 5648 (0–11,296) | 43,301 (0–86,602) |
| mRS 5 | 17,545 (0–35,090) | 7225 (0–14,450) | 40,781 (0–81,562) |
| mRS 6 | – | – | – |
mRS modified Rankin Scale, AUD Australian dollar
aThe range used for sensitivity analyses
bDerived from AVERT trial patient level data