Fig. 2.

Low painfulness and positive future intentions. A Study participants scored the pain they experienced during the ultrasound-guided inguinal lymph node biopsy on a 5-point Likert scale from 1 “not painful” to 5 “very painful” compared to venipuncture. The majority (91%) of responders scored either 1 or 2. Pain scores between the various groups did not differ by Fisher’s exact test. B Study participants reported their willingness to undergo a second biopsy and to encourage someone else to participate in a similar study by choosing yes, no, or neutral. The majority of all responders were willing to undergo a second biopsy (74%) and around half of the participants were willing to encourage someone else (54%), while around half of RA-risk individuals and healthy controls were neutral about encouraging someone else (54%). Overall includes RA, RA-risk, and HC individuals. RA, rheumatoid arthritis patients; RA-risk, individuals at risk for developing RA; HC, healthy controls