Table 2.
Characterization of included breast cancer patients who were eligible for screening and description of initial treatment phase by mode of detection
| All | Mode of detection | |||||||
|---|---|---|---|---|---|---|---|---|
| Screening participants | Unscreened (eligible) | |||||||
| Screen-detecteda | Interval-detected | |||||||
| 6065 | (100%) | 2049 | (33.8%) | 476 | (7.8%) | 3540 | (58.4%) | |
| Age at diagnosis | ||||||||
| Mean age at diagnosis (SD) | 61.2 | (6.0) | 62.0 | (5.8) | 61.9 | (6.0) | 60.6 | (6.0) |
| < 50 years at diagnosis | N/A | (0%) | N/A | (0%) | N/A | (0%) | N/A | (0%) |
| 50–69 years at diagnosis | 5950 | (98.1%) | 1970 | (96.1%) | 440 | (92.4%) | 3540 | (100%) |
| 70–79 years at diagnosis | 115 | (1.9%) | 79 | (3.9%) | 36 | (7.6%) | N/A | (0%) |
| 80 + years at diagnosis | N/A | (0%) | N/A | (0%) | N/A | (0%) | N/A | (0%) |
| Stage at diagnosis | ||||||||
| No affected lymph nodes/distant metastases | 5015 | (82.7%) | 1807 | (88.2%) | 392 | (82.4%) | 2816 | (79.5%) |
| Affected lymph nodes only | 788 | (13.0%) | 206 | (10.1%) | 72 | (15.1%) | 510 | (14.4%) |
| Distant metastases | 262 | (4.3%) | 36 | (1.8%) | 12 | (2.5%) | 214 | (6.0%) |
| Breast surgeryb | ||||||||
| Breast conserving surgery only | 4608 | (76.0%) | 1756 | (85.7%) | 348 | (73.1%) | 2504 | (70.7%) |
| Mastectomy | 1457 | (24.0%) | 293 | (14.3%) | 128 | (26.9%) | 1036 | (29.3%) |
| Both types of surgery | 610 | (10.1%) | 151 | (7.4%) | 61 | (12.8%) | 398 | (11.2%) |
| Two or more surgeries | 1606 | (26.5%) | 494 | (24.1%) | 145 | (30.5%) | 967 | (27.3%) |
| Neoadjuvant systemic therapy | ||||||||
| Yes | 501 | (8.3%) | 43 | (2.1%) | 43 | (9.0%) | 415 | (11.7%) |
| Adjuvant systemic therapyc | ||||||||
| Cytostatic drugs | 2758 | (45.5%) | 771 | (37.6%) | 236 | (49.6%) | 1751 | (49.5%) |
| Monoclonal antibody | 57 | (0.9%) | 6 | (0.3%) | 4 | (0.8%) | 47 | (1.3%) |
| Hormone therapy | 2823 | (46.5%) | 1086 | (53.0%) | 200 | (42.0%) | 1537 | (43.4%) |
| Radiotherapyd | ||||||||
| Within ten months after breast surgery | 4866 | (80.2%) | 1708 | (83.4%) | 381 | (80.0%) | 2777 | (78.4%) |
| Before breast surgery | 38 | (0.6%) | 3 | (0.1%) | 2 | (0.4%) | 33 | (0.9%) |
SD standard deviation, N/A not applicable
aBreast cancer was classified as “screen-detected” if a screening mammography and multidisciplinary case conference were coded in relevant time periods before and surrounding the diagnosis. It was classified as “interval-detected” if the woman had a screening mammography in the regular interval (two years) before diagnosis, but the criteria for “screen-detected” were not fulfilled. Patients without a screening mammography in the regular interval and aged 50–69 years at diagnosis were classified as unscreened, but eligible. The remaining patients were classified as “unscreened and ineligible” (not included in this table).Some patients may be diagnosed, e.g., at age 70 and screened at age 69
bWithin one year after diagnosis. Mastectomy includes those with both types of surgery. “Two or more surgeries” refers to additional breast conserving surgery/mastectomy in the first year after the first surgery
cThis refers to adjuvant systemic therapy initiated within four months after breast surgery
dThis refers to radiotherapy initiated within ten months after breast surgery