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. 2022 Feb 2;12:12. doi: 10.1186/s13578-022-00743-4

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Knockdown of YBX1 impeded the early embryo development in goat. A Schematic illustration of the knockdown experimental approach. B Characterization of YBX1 expression at the 8-cell stage YBX1 knockdown embryos. C No statistical change of YBX2 and YBX3 at the 8-cell stage YBX1 knockdown embryos. D Representative images of YBX1 knockdown and the control embryos at day 3 and day 7.5. The red arrow indicates developmental arrest embryos. The black asterisk indicates blastocysts. E, F Statistical analysis of embryos at day 7.5 and day 3 in YBX1 knockdown embryos