Table 4.
Top 15 hub genes with the highest interaction degrees in protein–protein interaction (PPI) network analysis.
| Gene ID | Description |
|---|---|
| Upregulated genes | |
| IL-6 | Interleukin 6 |
| CXCL8 | C-X-C motif chemokine ligand 8 |
| TLR4 | Toll like receptor 4 |
| STAT1 | Signal transducer and activator of transcription 1 |
| IL-1B | Interleukin 1 beta |
| CXCL10 | C-X-C motif chemokine ligand 10 |
| ICAM1 | Intercellular adhesion molecule 1 |
| JUN | Jun proto-oncogene, AP-1 transcription factor subunit |
| CCL5 | C-C motif chemokine ligand 5 |
| CCL2 | C-C motif chemokine ligand 2 |
| CD44 | CD44 molecule |
| Downregulated genes | |
| CDK1 | Cyclin dependent kinase 1 |
| UBE2C | Ubiquitin conjugating enzyme E2 C |
| CDC20 | Cell division cycle 20 |
| AURKB | Aurora kinase B |