Comparison 1. Any anticonvulsant versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Dropout	20	1695	Risk Ratio (M‐H, Random, 95% CI)	0.95 [0.86, 1.05]
2 Use of cocaine (self reported or objective)	11	867	Risk Ratio (M‐H, Random, 95% CI)	0.92 [0.84, 1.02]
3 Side effect	8	775	Risk Ratio (M‐H, Random, 95% CI)	1.39 [1.01, 1.90]
3.1 New subgroup	8	775	Risk Ratio (M‐H, Random, 95% CI)	1.39 [1.01, 1.90]
4 Craving	8	428	Std. Mean Difference (IV, Random, 95% CI)	‐0.25 [‐0.59, 0.09]
5 Severity of dependence (ASI)	6	290	Mean Difference (IV, Random, 95% CI)	0.03 [‐0.02, 0.08]
6 Severity of dependence (CGI‐O)	5	277	Mean Difference (IV, Random, 95% CI)	‐0.11 [‐0.42, 0.20]
7 Depression (HAM‐D)	3	80	Mean Difference (IV, Random, 95% CI)	1.80 [‐0.59, 4.19]
8 Anxiety (HAM‐A)	3	78	Mean Difference (IV, Random, 95% CI)	1.79 [‐1.02, 4.60]
9 Compliance	6	343	Risk Ratio (M‐H, Random, 95% CI)	1.01 [0.93, 1.08]
10 Compliance	5	426	Mean Difference (IV, Random, 95% CI)	1.42 [‐4.80, 7.64]