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. 2021 Oct 25;2021(10):CD013650. doi: 10.1002/14651858.CD013650.pub2

DAPPER.

Study name An Exploratory Study of Dapagliflozin for the Attenuation of Albuminuria in Patients with Heart Failure and Type 2 Diabetes Mellitus (DAPPER)
Methods Multicentre, randomised, open‐labelled, parallel‐group, standard treatment‐controlled study
Participants Type 2 Diabetes Mellitus patients with Chronic HF
Interventions Interventions: Dapagliflozin 5‐10 mg/day; SGLT2i
control: administration of anti‐diabetic drugs administered other than SGLT2i
Outcomes Primary objective:
Changes in the urinary albumin‐to‐creatinine ratio from the baseline after 2‐year treatment.
Secondary objectives:
(1) the safety of dapagliflozin and (2) the cardiovascular and renal efficacies of dapagliflozin.
Starting date 1 March 2017
Contact information Fumiki Yoshihara, dapper‐study@ml.ncvc.go.jp, Hyogo College Of Medicine
Notes UMIN000025102