DAPPER.
Study name | An Exploratory Study of Dapagliflozin for the Attenuation of Albuminuria in Patients with Heart Failure and Type 2 Diabetes Mellitus (DAPPER) |
Methods | Multicentre, randomised, open‐labelled, parallel‐group, standard treatment‐controlled study |
Participants | Type 2 Diabetes Mellitus patients with Chronic HF |
Interventions |
Interventions: Dapagliflozin 5‐10 mg/day; SGLT2i control: administration of anti‐diabetic drugs administered other than SGLT2i |
Outcomes |
Primary objective: Changes in the urinary albumin‐to‐creatinine ratio from the baseline after 2‐year treatment. Secondary objectives: (1) the safety of dapagliflozin and (2) the cardiovascular and renal efficacies of dapagliflozin. |
Starting date | 1 March 2017 |
Contact information | Fumiki Yoshihara, dapper‐study@ml.ncvc.go.jp, Hyogo College Of Medicine |
Notes | UMIN000025102 |