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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: J Magn Reson Imaging. 2021 Feb 15;54(1):166–174. doi: 10.1002/jmri.27550

Table 2.

ICCs with 95% CI of inter- and intra-observer agreement, and scan repeatability in morphologic measurements for each 3D VWI sequence.

ICC (95% CI) Lumen area Vessel wall
area
Lumen volume Vessel wall
volume
Plaque
burden
Percent
stenosis
Remodeling
ratio
Whole-brain Inter-observer 0.97 (0.94-0.99) 0.98 (0.94-0.99) 0.99 (0.94-0.99) 0.99 (0.98-0.99) 0.86 (0.71-0.93) 0.88 (0.77-0.94) 0.79 (0.59-0.89)
Intra-observer 0.99 (0.98-0.99) 0.99 (0.97-0.99) 0.99 (0.99-0.99) 0.99 (0.99-0.99) 0.95 (0.90-0.97) 0.96 (0.92-0.98) 0.95 (0.90-0.97)
Inter-scan 0.99 (0.98-0.99) 0.99 (0.96-0.99) 0.99 (0.97-0.99) 0.99 (0.99-0.99) 0.90 (0.78-0.95) 0.95 (0.90-0.97) 0.85 (0.72-0.93)
Targeted Inter-observer 0.81 (0.64-0.90) 0.95 (0.91-0.98) 0.96 (0.93-0.98) 0.99 (0.97-0.99) 0.71 (0.42-0.85) 0.86 (0.71-0.93) 0.76 (0.53-0.88)
Intra-observer 0.96 (0.93-0.98) 0.99 (0.98-0.99) 0.99 (0.94-0.99) 0.99 (0.98-0.99) 0.84 (0.69-0.92) 0.89 (0.79-0.94) 0.84 (0.69-0.92)
Inter-scan 0.84 (0.70-0.92) 0.97 (0.94-0.99) 0.99 (0.99-0.99) 0.99 (0.99-0.99) 0.82 (0.62-0.91) 0.94 (0.89-0.97) 0.80 (0.61-0.88)

Note: ICC= intra-class correlation coefficient; CI= confidence interval; VWI=vessel wall imaging.