TABLE 2.

Results of Adverse Events

Outcome of Interest	Studies	Participants	Effect Estimate	P	I 2
All studies
Cholangitis	7	520	2.17 [0.85, 5.54]	0.10	44%
Bile leakage	8	375	0.71 [0.23, 2.15]	0.54	0%
Pneumoperitoneum	5	374	0.86 [0.22, 3.35]	0.82	0%
Bleeding	6	509	1.61 [0.63, 4.14]	0.32	0%
Perforation	5	455	1.72 [0.46, 6.49]	0.42	0%
Stent dysfunction	8	433	0.55 [0.30, 1.02]	0.06	0%
Stent migration	7	340	0.79 [0.29, 2.14]	0.64	0%
Stent obstruction	6	338	0.48 [0.21, 0.94]	0.04	0%
Studies with FCSEMS
Cholangitis	3	99	10.29 [1.69, 62.74]	0.01	NS
Bile leakage	5	141	0.44 [0.04, 4.49]	0.49	0%
Pneumoperitoneum	2	135	0.72 [0.03, 18.08]	0.84	NS
Bleeding	1	39	Not estimable	NS	NS
Perforation	1	39	Not estimable	NS	NS
Stent dysfunction	4	177	0.72 [0.25, 2.10]	0.55	0%
Stent migration	3	61	0.73 [0.11, 5.07]	0.75	46%
Stent obstruction	3	99	0.39 [0.09, 1.76]	0.22	0%

FCSEMS indicates fully covered self-expandable metal stent.