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. 2021 Dec 16;117(2):311–318. doi: 10.14309/ajg.0000000000001584

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Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 2. — Proportion mediated of the total effect (OR 0.958 per 10 min total physical activity per day) for physical activity on nonalcoholic fatty liver disease (NAFLD). The shown variables were included 1 at a time in mediation analysis and were adjusted for age, sex, education, smoking, and alcohol consumption (model 2). In this analysis, even a slight positive effect estimate was observed for physical activity in relation to NAFLD with waist circumference as mediator, resulting in a proportion mediated of 1.08. *Indicates the particular parameter mediated a significant proportion of the total effect. Abbreviations: HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostatic model assessment of insulin resistance; SBP, systolic blood pressure; TG, triglycerides; waist C, waist circumference.