Table 3.
Study findings.
| Reference | Findings | |||||
|---|---|---|---|---|---|---|
| Condition | Result | |||||
| Scores* | P-values | Preop† | Postop† | Delta | ||
| Abbott et al. (2003) | ||||||
| Dysmenorrhoea | ||||||
| All stages | 9 vs 3.3 | <0.0001 | ||||
| Stage I EM | 8 vs 2 | <0.0001 | ||||
| Stage II EM | 8 vs 4.5 | <0.0001 | ||||
| Stage III EM | 9 vs 3.5 | <0.0001 | ||||
| Stage IV EM | 9 vs 2 | <0.0001 | ||||
| Non-menstrual pelvic pain | ||||||
| All stages | 8 vs 3 | <0.0001 | ||||
| Stage I EM | 6 vs 3 | 0.036 | ||||
| Stage II EM | 6 vs 3.3 | <0.0001 | ||||
| Stage III EM | 6 vs 2.9 | 0.046 | ||||
| Stage IV EM | 7 vs 2.4 | <0.0001 | ||||
| Dyspareunia | ||||||
| All stages | 7 vs 0 | <0.0001 | ||||
| Stage I EM | 7 vs 2.6 | 0.002 | ||||
| Stage II EM | 5.5 vs 1.7 | 0.005 | ||||
| Stage III EM | 6 vs 0 | 0.004 | ||||
| Stage IV EM | 6 vs 0 | <0.0001 | ||||
| Dyschezia | ||||||
| All stages | 7 vs 2 | <0.0001 | ||||
| Stage I EM | 6 vs 3.1 | 0.035 | ||||
| Stage II EM | 6 vs 2.7 | 0.006 | ||||
| Stage III EM | 4 vs 0 | 0.12 | ||||
| Stage IV EM | 5 vs 2 | 0.002 | ||||
| Chopin et al. (2005) | ||||||
| USL (n = 78) | ||||||
| Dysmenorrhea (n = 68) | 0.0001 | 7.68 ± 2.08 (0–10) | 3.31 ± 3.31 (0–10) | 4.36 ± 3.61 | ||
| Deep dyspareunia (n = 61) | 0.0001 | 6.41 ± 2.47 (0–10) | 2.12 ± 2.71 (0–10) | 4.30 ± 3.29 | ||
| Dyschezia (n = 39) | 0.0001 | 6.44 ± 2.59 (0–10) | 2.72 ± 3.12 (0–10) | 3.72 ± 4.00 | ||
| LUTS (n = 21) | 0.0011 | 5.52 ± 0.69 (2–8) | 2.29 ± 3.23 (0–8) | 3.24 ± 3.02 | ||
| CPP (n = 36) | 0.0001 | 7.36 ± 1.46 (3–10) | 3.25 ± 3.83 (0–10) | 4.11 ± 3.34 | ||
| Vagina (n = 25) | ||||||
| Dysmenorrhea (n = 23) | 0.0001 | 8.00 ± 1.48 (5–10) | 2.82 ± 3.33 (0–9) | 5.17 ± 3.70 | ||
| Deep dyspareunia (n = 21) | 0.0001 | 6.77 ± 1.73 (4–10) | 1.62 ± 3.03 (0–9) | 5.14 ± 2.97 | ||
| Dyschezia (n = 17) | 0.0007 | 6.77 ± 2.17 (4–10) | 2.35 ± 3.10 (0–8) | 4.41 ± 3.20 | ||
| LUTS (n = 4) | 0.0679 | 4.50 ± 1.73 (3–7) | 0.00 ± 0.00 (0–0) | 4.50 ± 1.73 | ||
| CPP (n = 8) | 0.0171 | 7.63 ± 1.60 (5–10) | 1.62 ± 3.11 (0–9) | 6.00 ± 3.25 | ||
| Bladder (n = 13) | ||||||
| Dysmenorrhea (n = 13) | 0.0022 | 9.23 ± 1.09 (7–10) | 2.23 ± 2.95 (0–7) | 7.00 ± 3.27 | ||
| Deep dyspareunia (n = 9) | 0.0117 | 7.56 ± 2.13 (4–10) | 2.44 ± 2.60 (0–7) | 5.11 ± 3.76 | ||
| Dyschezia (n = 4) | 0.0679 | 7.50 ± 2.08 (5–10) | 0.00 ± 0.00 (0–0) | 7.50 ± 2.08 | ||
| LUTS (n = 12) | 0.022 | 7.50 ± 2.24 (3–10) | 0.00 ± 0.00 (0–0) | 7.50 ± 2.24 | ||
| CPP (n = 1) | 5.0 (5–5) | 0.00 (0–0) | 5.0 | |||
| Intestine (n = 16) | ||||||
| Dysmenorrhea (n = 16) | 0.0004 | 9.00 ± 0.97 (8–10) | 1.94 ± 2.77 (0–8) | 7.06 ± 2.82 | ||
| Deep dyspareunia (n = 13) | 0.0015 | 6.77 ± 2.13 (3–10) | 2.08 ± 2.75 (0–9) | 4.69 ± 2.32 | ||
| Dyschezia (n = 11) | 0.0033 | 6.91 ± 2.55 (3–10) | 1.09 ± 2.07 (0–6) | 5.82 ± 2.71 | ||
| LUTS (n = 4) | 0.0679 | 7.00 ± 1.83 (5–9) | 1.00 ± 2.00 (0–4) | 6.00 ± 3.16 | ||
| CPP (n = 6) | 0.0277 | 9.17 ± 0.98 (8–10) | 3.50 ± 3.89 (0–8) | 5.67 ± 4.13 | ||
| Banerjee et al. (2006) | Difference pre- to post-operative scores: 5.2 points ± 3.6 for dysmenorrhea, 4.6 points ± 3.1 for deep dyspareunia, 4.4 points ± 3.7 for painful defecation during menstruation, 4.9 ± 3.2 for LUTS during menses, and 4.6 points ± 3.4 for noncyclic chronic pelvic pain. Comparable results observed for patients in each group according to the surgical classification of their DIE lesions: USL (n = 78 patients); vagina (n = 25 patients); bladder (n = 13 patients); and intestine (n = 16 patients). | |||||
| Banerjee et al. (2006) | Difference pre to postoperative scores: 5.2 points ± 3.6 for dysmenorrhea, 4.6 points ± 3.1 for deep dyspareunia, 4.4 points ± 3.7 for painful defecation during menstruation, 4.9 ± 3.2 for lower urinary tract symptoms during menses, and 4.6 points ± 3.4 for noncyclic chronic pelvic pain. Comparable results observed for patients in each group according to the surgical classification of their DIE lesions: USL (n = 78 patients); vagina (n = 25 patients); bladder (n = 13 patients); and intestine (n = 16 patients). |
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| Milingos et al. (2006) | Postoperatively dysmenorrhea improved in 43% of cases in group 1 (superficial endometriosis), vs 66% of cases in group 2 (deep endometriosis) (P = 0.0037). For deep dyspareunia, improvement was reported by 33% in group 1, vs 67% in group 2 (P = 0.074). Scores for Improvement in non-menstrual pain was not significantly different between the two groups (67% vs 56%). Global pain scores (s.d., pre vs post-operative) were 17.5 (7.8) vs 16.1 (6.7), P = 0.43 for superficial endometriosis, and 19.2 (7.2) vs 14.5 (8.9), P = 0.004 for deep endometriosis ± superficial (figures not given for deep alone). | |||||
| Ghai et al. (2020) | Higher proportion of women with severe endometriosis (n = 86/96) than women with superficial endometriosis (77/102; P = 0.0089) respond to surgery. Women with severe endometriosis were more likely to respond to surgery of they have higher preoperative EPH 30 pain scores (median 66, range 24–83) as compared to lower scores (median 50; range 20.5–63.6). In this group response to surgery was associated with lower scores for ‘feeling of control’ (60.25; range 47.7–72.7 vs 62.5 vs 45.8–70.8) |
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*Pain scores (median VAS baseline versus follow-up 2–5 years) were all significantly reduced for conditions presented; †values presented as mean ± s.d. (range).
EM, endometriosis; LUTS, lower urinary tract symptoms.
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