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. 2022 Jan 27;119(5):e2115895119. doi: 10.1073/pnas.2115895119

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Copyright © 2022 the Author(s). Published by PNAS.

This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).

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Fig. 2. — F-actin controls the dynamics of the extensile MT network. (A) Kinesin motors drive the reorganization of both F-actin and MT networks. (B) The mean speed of the autonomous flows decreases with increasing F-actin concentration. (C) The spatial velocity–velocity correlation function of the autonomous flows is independent of the F-actin concentration. (C, Inset) The correlation lengthscales, extracted from fits to exponential decay, are independent of F-actin concentration. (D) Upon cessation of motor-driven flow, F-actin relaxes away from its out-of-equilibrium configuration while the MT bundles remain fixed (Movie S3). (E) After motor-driven activity halts at 1.8 hours, the spatial correlation between the MT and F-actin concentration fields decreases as a function of time.