Table 2.
Information on potential targets and the topological attributes.
No. | Gene name | Protein name | UniProt ID | Degree |
1 | VEGFA | Vascular endothelial growth factor A | P15692 | 50 |
2 | TNF | Tumor necrosis factor | P01375 | 50 |
3 | AKT1 | RAC-alpha serine/threonine-protein kinase | P31749 | 49 |
4 | IL6 | Interleukin-6 | P05231 | 49 |
5 | MAPK1 | Mitogen-activated protein kinase 1 | P28482 | 46 |
6 | PTGS2 | Prostaglandin G/H synthase 2 | P35354 | 43 |
7 | EGFR | Epidermal growth factor receptor | P00533 | 42 |
8 | JUN | Transcription factor AP-1 | P05412 | 42 |
9 | IL1B | Interleukin-1 beta | P01584 | 42 |
10 | CCL2 | C-C motif chemokine 2 | P13500 | 42 |
11 | EGF | Pro-epidermal growth factor | P00533 | 41 |
12 | MAPK8 | Mitogen-activated protein kinase 8 | P01133 | 41 |
13 | IL10 | Interleukin-10 | P22301 | 40 |
14 | CXCL8 | Interleukin-8 | P10145 | 40 |
15 | NOS3 | Nitric-oxide synthase, endothelial | P29474 | 39 |
16 | PPARG | Peroxisome proliferator activated receptor gamma | P37231 | 38 |
17 | MAPK14 | Mitogen-activated protein kinase 14 | Q16539 | 37 |
18 | ESR1 | Estrogen receptor | P03372 | 37 |
19 | MMP2 | 72 kDa type IV collagenase | P08253 | 36 |
20 | PTEN | Phosphatase and tensin homolog deleted on chromosome 10 | P60484 | 35 |