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. 2022 Feb 4;101(5):e28729. doi: 10.1097/MD.0000000000028729

Table 1.

Comparison of data between sacubitril valsartan group and valsartan group.

Characteristic Salkubatroxartan group (84) Valsartan group (86) t or χ2 P
Age (yr), mean ± SD 62.29 ± 12.82 63.49 ± 11.61 −0.642 .522
Gender (male), n (%) 52 (61.90%) 56 (65.12%) 0.664 .750
Hypertension, n (%) 56 (66.67%) 52 (60.47%) 0.705 .429
SP (mm Hg) mean ± SD 124.90 ± 18.68 128.91 ± 16.52 −1.481 .141
Severity of myocardial infarction, n (%)
 Single vessel lesion 7 (8.33%) 11 (12.79%) 0.892 .456
 Double vessel lesion 20 (23.81%) 19 (22.62%) 0.071 .856
 Three vessel lesion 56 (66.67%) 56 (65.12%) 0.045 .872
HbA1c (%), mean ± SD 8.40 ± 1.67 8.05 ± 1.22 1.567 .119
FBG (mmol/L), mean ± SD 10.41 ± 3.69 9.91 ± 3.54 0.902 .368
NT-proBNP (ng/L), mean ± SD 679.10 ± 623.32 666.14 ± 407.78 0.161 .872
SCr (umol/L), mean ± SD 69.69 ± 21.52 75.05 ± 25.77 −1.468 .144
LDL-C (mmol/L), mean ± SD 2.43 ± 0.83 2.54 ± 0.79 −0.825 .410
Killip classification, n (%)
 I 22 (26.19%) 24 (27.91%) 0.801 .864
 II 26 (30.95%) 26 (30.23%) 0.919 1.000
 III 14 (16.67%) 16 (18.60%) 0.740 .841
 IV 22 (26.19%) 20 (23.26%) 0.657 .723
Drug use during treatment, n (%)
 β-blocker 76 (90.48%) 74 (86.05%) 0.370 .477
 Spironolactone 26 (30.95%) 30 (34.88%) 0.586 .627
 Digitalis 32 (38.10%) 30 (34.88%) 0.664 .750
 Diuretic 2 (2.38%) 2 (2.33%) 0.981 1.000
LVEF (%), mean ± SD 44.69 ± 4.60 44.65 ± 4.42 0.057 .955
LVDD (mm), mean ± SD 51.52 ± 6.20 50.05 ± 5.62 1.552 .123

FBG = fasting blood glucose, HbA1c = hemoglobin A1c, LDL-C = low density lipoprotein-cholestero, LVDD = left ventricular end diastolic dimension, LVEF = left ventricular ejection fraction, NT-proBNP = N-terminal pro-brain natriuretic peptide, SCr = serum creatinine, SP = systolic pressure.