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. 2022 Jan 31;11(1):2027148. doi: 10.1080/2162402X.2022.2027148

Figure 3.

Figure 3.

Compartmental IL2 levels and their association with presence of TLS. (a) Comparison of PDA patients with “TLS” (n = 13) versus “No TLS” (n = 36) regarding the stromato-tumor (left) and stroma-to-serum IL2 gradient (right). (b) Scatter dot plots comparing Serum IL2, Serum CRP, Serum WBC and CA 19–9 concentrations of PDA patients with “TLS” (IL2: n = 13; CRP, WBC, CA 19–9: n = 17) versus “No TLS” (n = 38). *p ≤ .05, ***p ≤ .005. TLS = Tertiary lymphoid structures, IL2 = Interleukin-2, CRP = C-reactive protein, WBC = White blood cells, CA 19-9 =  Carbohydrate antigen 19–9, PDA = Pancreatic ductal adenocarcinoma.