Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 31;23(1):76–88. doi: 10.1080/15384047.2021.2017222

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

PMC Copyright notice

Figure 5. — miR-135b-5p targeted FOXO1. (a) Venn map of StarBase, RNAInter, Targetscan, and miRDB database were used to predict the connections of miR-135b-5p downstream target genes; (b) Co-expression network of candidate genes; (c–d) ECORI Pan-Cer database was used to analyze the expression pattern of FOXO1 in COAD and its correlation with miR-135b-5p; (e) StarBase was used to predict and analyze the targeted binding relationship between miR-135b-5p and FOXO1; (f) The targeted binding was verified by dual-luciferase reporter assay; (g) The expression of FOXO1 mRNA in SW480/HCT116 co-cultured with HUVECs was detected by RT-qPCR. Three cell tests were performed and the data were expressed as mean ± standard deviation. Independent t test was used for comparison of the data in F and one-way ANOVA was used for comparison of the data in G. Tukey’s multiple comparisons test was used for the post hoc test. **P < .01.

The revised figure 5 in the attachment shall prevail. Thank you.