Table 2.
Severity of TDP-43 pathology in each region in ALS cases
| TDP-43 pathology scores | ||
|---|---|---|
| Median | IQRs | |
| 01 Spinal cord | 2 | 2-3 |
| 02 Motor cortex | 2 | 0.5-2 |
| 03 Medulla | 1 | 0.625-2 |
| 04 Caudate/Putamen | 1 | 0-1 |
| 05 Midbrain | 0.5 | 0-1 |
| 06 Globus Pallidus | 0.5 | 0-1 |
| 07 Anterior cingulate | 0.5 | 0-1 |
| 08 Thalamus/subthalamus | 0.5 | 0-1 |
| 09 Pons | 0.5 | 0-1 |
| 10 Substantia nigra | 0.5 | 0-1 |
| 11 Middle frontal cortex | 0 | 0-1 |
| 12 Amygdala | 0 | 0-0.75 |
| 13 Angular gyrus | 0 | 0-0.5 |
| 14 CA1/subiculum | 0 | 0-0.5 |
| 15 Entorhinal cortex | 0 | 0-0.5 |
| 16 Superior/middle temporal cortex | 0 | 0-0.5 |
| 17 Dentate gyrus | 0 | 0-0.375 |
| 18 Cerebellum | 0 | 0-0 |
| 19 Locus coeruleus | 0 | 0-0 |
| 20 Occipital cortex | 0 | 0-0 |