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. 2021 Apr 29;10(1):810–821. doi: 10.1080/22221751.2021.1917309

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Cross-inhibitory activity of EK1C4 on HIV-1 cell fusion and pseudovirus infection. Inhibition of the Env-mediated cell–cell fusion activity of HIV-1_NL4-3 (A), HIV-1_JRFL (B), and HIV-1_SF162 (C) was determined by a DSP-based cell–cell fusion assay. Inhibition of HIV-1_NL4-3 (D), HIV-1_JRFL (E), and HIV-1_SF162 (F), VSV-G (G), H5N1 (H), and H7N9 (I) pseudoviruses were determined by a single-cycle infection assay. The experiments were repeated three times, and data are expressed as means ± SD while the mean IC₅₀ values are shown.