Table 2.

The agonistic, antagonistic, and partial agonist activities of 1g of product presented as hormonal equivalent concentrations relative to their respective positive controls.

RGA	Sample 1 (Hair lotion)	Sample 2 (Leave-in conditioner)	Sample 3 (Leave-in conditioner)	Sample 4 (Hair oil)	Sample 5 (Root stimulator)	Sample 6 (Hair oil)
Estrogen	Agonist with additive response 12.5–20ng/g EEQ	No response observed	Partial agonist: Agonist 5–7.5ng/g EEQ Antagonist reducing EEQ by 20–25ng/g	Antagonist reducing EEQ by 22.5–25ng/g	Agonist 15ng/g EEQ	Antagonist – difficult to estimate due to toxicity. reducing EEQ by 25ng/g (in all dilutions)
Androgen	No response observed	Antagonist reducing TEQ by 145ng/g	Antagonist reducing TEQ by 145ng/g	Antagonist reducing TEQ by 131ng/g	No response observed	Antagonist reducing TEQ by 145ng/g
Progesterone	Antagonist reducing PEQ by 75ng/g	Partial agonist: Agonist 250ng/g PEQ Antagonist reducing PEQ by 125ng/g	Antagonist reducing PEQ by 200ng/g	Partial agonist: Agonist 50ng/g PEQ Antagonist reducing PEQ by 175–225ng/g	No response observed	No response observed
Glucocorticoid	No response observed	Antagonist reducing GEQ by 2500ng/g	Antagonist reducing GEQ by 2000ng/g	Antagonist reducing GEQ by 15002000ng/g	Antagonist reducing GEQ by 500ng/g	No response observed

Abbreviations: EEQ, Estrogen Equivalents of 17beta-estradiol; TEQ, Testosterone Equivalents of testosterone; PEQ, Progesterone Equivalents of progesterone; GEQ, Glucocorticoid Equivalents of hydrocortisol