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. 2022 Feb 4;71(5):171–176. doi: 10.15585/mmwr.mm7105a3

TABLE 3. Behavioral and social drivers of COVID-19 vaccination, by sexual orientation and gender identity — National Immunization Survey Adult COVID Module, United States, August 29–October 30, 2021.

Central attitudes and experiences % (95% CI)*
Overall Sexual orientation
Gender identity
Heterosexual/ Straight Gay or lesbian Bisexual Something else Not transgender or nonbinary Transgender or nonbinary
Total
153,062
132,608
3,941
4,395
2,532
136,929
5,594
Concerned about COVID–19 (very or moderately)
48.5 (48.0–49.0)
48.1 (47.6–48.7)
56.8 (53.5–60.0)
51.3 (48.5–54.1)
52.8 (48.9–56.6)
48.4 (47.9–49.0)
49.4 (46.8–52.0)
Male
42.6 (41.9–43.4)
42.2 (41.5–43.0)
55.0 (50.8–59.3)
42.0 (37.1–47.1)
45.3 (39.4–51.4)
NA
NA
Female
53.9 (53.2–54.6)
54.0 (53.2–54.7)
59.1 (53.9–64.2)
54.9 (51.6–58.3)
57.8 (52.8–62.6)
NA
NA
Confidence in vaccine safety (completely or very)
64.4 (63.8–64.9)
63.9 (63.3–64.4)
76.3 (73.1–79.3)
70.4 (67.6–73.1)
69.3 (65.5–72.8)
64.7 (64.2–65.2)
62.8 (60.2–65.4)
Male
64.1 (63.4–64.9)
63.2 (62.4–64.0)
82.4 (78.3–85.9)
76.3 (71.0–80.8)
72.7 (67.2–77.6)
NA
NA
Female
64.6 (63.9–65.3)
64.5 (63.7–65.3)
67.4 (62.2–72.3)
68.1 (64.7–71.4)
66.9 (61.8–71.7)
NA
NA
Vaccine important to protect self (very or somewhat)
80.9 (80.5–81.3)
80.4 (80.0–80.9)
90.8 (88.5–92.7)
86.8 (84.7–88.6)
83.5 (80.0–86.5)
80.7 (80.3–81.2)
83.2 (81.1–85.1)§
Male
77.7 (77.0–78.3)
76.9 (76.2–77.6)
92.9 (89.9–95.1)
87.6 (82.7–91.2)
80.8 (75.4–85.3)
NA
NA
Female
83.9 (83.4–84.5)
83.9 (83.2–84.4)
87.8 (83.9–90.9)
86.4 (84.2–88.5)
85.4 (80.5–89.2)
NA
NA
Had friends/family who were vaccinated (almost all or many)
70.2 (69.7–70.6)
70.0 (69.5–70.5)
76.4 (73.4–79.2)
71.2 (68.4–73.8)
72.7 (69.1–76.0)
70.6 (70.1–71.1)
67.6 (65.1–70.1)§
Male
68.3 (67.6–69.0)
67.8 (67.1–68.6)
79.3 (75.5–82.8)
71.5 (66.2–76.4)
71.4 (65.9–76.4)
NA
NA
Female
71.9 (71.3–72.6)
72.1 (71.4–72.8)
72.4 (67.4–76.9)
71.0 (67.7–74.1)
73.5 (68.7–77.8)
NA
NA
Difficulty getting vaccinated (very or somewhat)
14.9 (14.6–15.3)
14.9 (14.6–15.3)
18.9 (16.3–21.8)
12.0 (10.4–13.8)
16.1 (13.4–19.2)
15.1 (14.7–15.5)
13.2 (11.6–15.0)§
Health care provider recommended the vaccine
41.2 (40.7–41.7)
41.3 (40.8–41.9)
47.3 (44.1–50.6)
38.1 (35.4–40.8)
40.3 (36.7–44.1)
41.3 (40.8–41.8)
38.4 (35.9–40.9)§
Male
37.5 (36.8–38.2)
37.3 (36.5–38.0)
49.0 (44.7–53.3)
34.2 (29.3–39.5)
37.2 (31.7–43.0)
NA
NA
Female
44.7 (44.0–45.4)
45.3 (44.6–46.1)
45.0 (40.0–50.1)
39.6 (36.4–42.8)
42.5 (37.8–47.3)
NA
NA
Work or school requires the vaccine 22.6 (22.1–23.0) 22.1 (21.7–22.6) 26.4 (23.8–29.2) 26.5 (24.2–29.0) 29.4 (25.8–33.3) 22.5 (22.1–23.0) 25.9 (23.6–28.2)§

Abbreviation: NA = not applicable.

* Weighted estimate.

Compared with heterosexual persons, p<0.05.

§ Compared with persons who were not transgender or nonbinary, p<0.05.

Vaccinated respondents were asked, “How difficult was it for you to get a COVID-19 vaccine?”; unvaccinated respondents were asked “How difficult would it be for you to get a COVID-19 vaccine?