Table 3. Summary of acute diagnostic assays employed in included studies, by species.
Number of Included Studies that Used the Following Methods for Detection of Acute RVFV Infection | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Species | IgM | IgM, direct1 | IgM,PCR | IgM, PCR, direct1 | IgM, PCR IgG SC2 | IgM, IgG SC2 | PCR IgG SC2 | Direct1 only | PCR only | PCR, direct1 | IgG SC2only | Total |
Livestock | 26 | 0 | 4 | 0 | 1 | 3 | 2 | 0 | 5 | 0 | 3 | 44 |
Humans | 21 | 2 | 23 | 4 | 2 | 0 | 0 | 2 | 9 | 1 | 0 | 64 |
Humans, livestock | 1 | 1 | 5 | 3 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 12 |
Humans, livestock, wildlife | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Wildlife | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 4 |
Method Total | 48 | 3 | 33 | 8 | 4 | 3 | 2 | 3 | 15 | 2 | 4 |
1Direct: Direct detection methods include immunofluorescence assay, cell culture (virus isolation), electron microscopy, and immunohistochemistry
2SC: IgG Seroconversion of IgG (positive IgG during the study period AND a previously documented negative status from the same individual)