Table 2.
Enriched KEGG pathways for DMGs
| Dataset | Pathway | KEGG ID | ORA (gene ratio)a | Wilcoxb | KS-bootc |
|---|---|---|---|---|---|
| L2:L1 | Cell adhesion molecules (CAMs) | sasa04514 | RS+GB (38/616), P+ GB (32/517), Gene body (31/420), Intron (26/339) | RS+GB, Flanks | RS+GB, Flanks, P+ GB, Gene body, Exon |
| RNA degradation | sasa03018 | - | RS+GB | P+ GB | |
| Glycosaminoglycan degradation | sasa00531 | P1K (2/21) | - | - | |
| Mitophagy – animal | sasa04137 | Promoter (7/99), P1K (3/21) | - | - | |
| Apelin signalling pathway | sasa04371 | P+ GB (28/517) | - | - | |
| Starch and sucrose metabolism | sasa00500 | P6K (4/74) | - | - | |
| L3:L1 | Cell adhesion molecules (CAMs) | sasa04514 | RS+GB (37/573), P+ GB (30/465), Gene body (27/388), Intron (27/320) | RS+GB | RS+GB, P+ GB, Gene body, Intron |
| ECM-receptor interaction | sasa04512 | Intron (15/320) | - | - | |
| mTOR signalling pathway | sasa04150 | - | RS+GB, Gene body, Intron | RS+GB, P+ GB, Gene body, Intron | |
| C-type lectin receptor signalling pathway | sasa04625 | - | RS+GB, Exon | Exon |
aAdjusted p-values < 0.01 were used to define ORAs. bWilcoxon signed rank test (adjusted p-value < 0.05). cKolmogorov–Smirnov test with bootstrap p-value calculation (adjusted p-value < 0.01).