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. 2020 Dec 8;16(11):1201–1216. doi: 10.1080/15592294.2020.1853402

Figure 4.

Figure 4.

Effects of guadecitabine on expression of selected genes. (a–c) Basal mRNA expression levels of FXYD6, PDHX and UEB4A measured by real-time RT-PCR in platinum resistant (r) OVCAR5_R, A2780_R and SKOV3_R; (d–f) expression levels of IRF9, EVI2A and CCL19 on parental and cisplatin-resistant (R) A2780, SKOV3, and OVCAR5 treated with guadecitabine (100 nM) for 72 hours, and (g) OVCAR3 cells treated with the guadecitabine (100 nM) for 72 hours. Bars represent mean ± SD, n = 3 (* P < 0.05, ** P < 0.01)