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. 2022 Jan 27;2022:9943571. doi: 10.1155/2022/9943571

Table 2.

Top scored three Molecular Complex Detection (MCODE) clusters and significantly enriched pathways. FDR: false discovery rate.

MCODE Genes Interactions Gene symbols Enriched pathways (FDR < 0.05)
1 61 1791 RPS27, RPS23, RPS14, RPL10L, RPL10, EIF3D, EIF3B, RPL24, RPS21, RPSA, NHP2L1, FBL, RPL7A, RPS16, RPS10, RPL19, RPL13, RPL4, RPS7, RPS3, RPL38, RPS26, RPL6, RPS4X, RPS3A, RPL18, RPL29, RPL14, RPS5, RPL35, RPS25, RPL3, RPL10A, RPS24, RPS15A, RPL12, RPL26, RPS19, RPL32, RPL18A, RPS11, RPL15, RPL36, RPL22, RPLP0, RPS2, RPL21, RPL13A, EIF4B, NSA2, EIF3K, EIF3F, EIF4A1, GNB2L1, EIF3A, EEF1B2, EIF3G, EEF1A1, EEF1G, EEF2, RPS6 hsa03010:ribosome

2 14 45 SPARC, GABBR1, TIMP1, CNR2, GNG7, CCL5, TGFB1, GNG11, GNG8, F13A1, P2RY12, CLU, ITIH4, ACTN1 NA

3 28 86 HLA-DPA1, HLA-DPB1, LSM7, HIST1H2AM, DNM3, CTTN, HIST1H2AI, HIST1H2BF, HLA-DRB1, HLA-DRB5, CIITA, H2AFJ, HIST1H2BK, HIST1H2AA, HIST1H2BB, HIST1H2AE, HIST2H2BE, RAN, HLA-DMA, DAB2, LDLRAP1, HLA-DQA1, SNRPD1, REPS1, HLA-DQB1, STON2, PPIH, RBMX hsa05322:systemic lupus erythematosus
hsa05310:asthma
hsa05332:graft-versus-host disease
hsa05330:allograft rejection
hsa04940:type I diabetes mellitus
hsa04612:antigen processing and presentation
hsa04672:intestinal immune network for IgA production
hsa05320:autoimmune thyroid disease
hsa05150:Staphylococcus aureus infection
hsa05416:viral myocarditis
hsa05321:inflammatory bowel disease (IBD)
hsa05145:toxoplasmosis
hsa05034:alcoholism
hsa05140:leishmaniasis
hsa05323:rheumatoid arthritis
hsa05164:influenza A
hsa05152:tuberculosis
hsa04514:cell adhesion molecules (CAMs)
hsa04145:phagosome
hsa05166:HTLV-I infection
hsa05168:herpes simplex infection