Table 2.
MCODE | Genes | Interactions | Gene symbols | Enriched pathways (FDR < 0.05) |
---|---|---|---|---|
1 | 61 | 1791 | RPS27, RPS23, RPS14, RPL10L, RPL10, EIF3D, EIF3B, RPL24, RPS21, RPSA, NHP2L1, FBL, RPL7A, RPS16, RPS10, RPL19, RPL13, RPL4, RPS7, RPS3, RPL38, RPS26, RPL6, RPS4X, RPS3A, RPL18, RPL29, RPL14, RPS5, RPL35, RPS25, RPL3, RPL10A, RPS24, RPS15A, RPL12, RPL26, RPS19, RPL32, RPL18A, RPS11, RPL15, RPL36, RPL22, RPLP0, RPS2, RPL21, RPL13A, EIF4B, NSA2, EIF3K, EIF3F, EIF4A1, GNB2L1, EIF3A, EEF1B2, EIF3G, EEF1A1, EEF1G, EEF2, RPS6 | hsa03010:ribosome |
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2 | 14 | 45 | SPARC, GABBR1, TIMP1, CNR2, GNG7, CCL5, TGFB1, GNG11, GNG8, F13A1, P2RY12, CLU, ITIH4, ACTN1 | NA |
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3 | 28 | 86 | HLA-DPA1, HLA-DPB1, LSM7, HIST1H2AM, DNM3, CTTN, HIST1H2AI, HIST1H2BF, HLA-DRB1, HLA-DRB5, CIITA, H2AFJ, HIST1H2BK, HIST1H2AA, HIST1H2BB, HIST1H2AE, HIST2H2BE, RAN, HLA-DMA, DAB2, LDLRAP1, HLA-DQA1, SNRPD1, REPS1, HLA-DQB1, STON2, PPIH, RBMX | hsa05322:systemic lupus erythematosus hsa05310:asthma hsa05332:graft-versus-host disease hsa05330:allograft rejection hsa04940:type I diabetes mellitus hsa04612:antigen processing and presentation hsa04672:intestinal immune network for IgA production hsa05320:autoimmune thyroid disease hsa05150:Staphylococcus aureus infection hsa05416:viral myocarditis hsa05321:inflammatory bowel disease (IBD) hsa05145:toxoplasmosis hsa05034:alcoholism hsa05140:leishmaniasis hsa05323:rheumatoid arthritis hsa05164:influenza A hsa05152:tuberculosis hsa04514:cell adhesion molecules (CAMs) hsa04145:phagosome hsa05166:HTLV-I infection hsa05168:herpes simplex infection |