Table 1.
Left ventricular functional parameters of rats on 31st day.
| Control | DOX | DOX+QL | |
|---|---|---|---|
| LVEDd (mm) | 6.11 ± 0.23 | 6.53 ± 0.40 | 6.49 ± 0.22 |
| LVEDs (mm) | 2.55 ± 0.11 | 4.42 ± 0.29∗∗∗ | 3.61 ± 0.26# |
| LVPWd (mm) | 1.67 ± 0.10 | 1.67 ± 0.07 | 1.85 ± 0.12 |
| LVPWs (mm) | 3.09 ± 0.20 | 2.25 ± 0.12∗ | 3.02 ± 0.16# |
| LVAWd (mm) | 1.84 ± 0.09 | 1.58 ± 0.09 | 1.71 ± 0.11 |
| LVAWs (mm) | 3.19 ± 0.11 | 2.40 ± 0.15∗∗∗ | 2.67 ± 0.16 |
| FS (%) | 58.20 ± 1.38 | 32.43 ± 1.77∗∗∗ | 44.71 ± 2.92## |
| EF (%) | 91.50 ± 0.69 | 66.29 ± 2.39∗∗∗ | 80.29 ± 2.93### |
Data are presented as mean ± SD. DOX vs. control ∗P < 0.05 and ∗∗∗P < 0.001. DOX+QL vs. DOX #P < 0.05, ##P < 0.01, and ###P < 0.001 by two-way repeated-measures ANOVA with LSD post hoc test. LVEDd: left ventricular end-diastolic diameter; LVEDs: left ventricular end-systolic diameter; LVPWd: left ventricular posterior wall thickness in end-diastole; LVPWs: left ventricular posterior wall thickness in end-systole; LVAWd: left ventricular anterior wall thickness in end-diastole; LVAWs: left ventricular anterior wall thickness in end-systole; EF: left ventricular ejection fraction; FS: left ventricular fractional shortening.