Table 6.
Registered clinical trials on the use of FVP, RDV and their combination in Covid-19 patients.
| Drug | ClinicalTrials.gov Identifier | Title | Status | n | Country |
|---|---|---|---|---|---|
| FVP | NCT04336904 | Clinical Study to Evaluate the Performance and Safety of Favipiravir in COVID-19 | Active, not recruiting | 100 | Italy |
| NCT04474457 | Efficacy and Safety of Favipiravir in the Treatment of COVID-19 Patients Over 15 Years of Age | Active, not recruiting | 1000 | Turkey | |
| NCT04359615 | Favipiravir in Hospitalized COVID-19 Patients (FIC) | Not yet recruiting | 40 | Iran | |
| NCT04425460 | A Multi-center, Randomized, Double-blind, Placebo-controlled, Phase 3 Study Evaluating Favipiravir in Treatment of COVID-19 | Not yet recruiting | 256 | China, Germany, Romania | |
| NCT04529499 | Clinical Trial Evaluating the Efficacy and Safety of Favipiravir in Moderate to Severe COVID-19 Patients | Active, not recruiting | 780 | Kuwait | |
| NCT04434248 | An Adaptive Study of Favipiravir Compared to Standard of Care in Hospitalized Patients With COVID-19 | Active, not recruiting | 330 | Russia | |
| RDV | NCT04713176 | Efficacy and Safety of DWJ1248 With Remdesivir in Severe COVID-19 Patients | Recruiting | 1022 | South Korea |
| NCT04582266 | PK and Safety of Remdesivir for Treatment of COVID-19 in Pregnant and Non-Pregnant Women in the US | Recruiting | 40 | USA | |
| NCT04647695 | IFN-beta 1b and Remdesivir for COVID19 | Recruiting | 100 | China | |
| NCT04854837 | Safety of Remdesivir Treatment in COVID-19 Patients Requiring Hemodialysis (REM-HD) | Recruiting | 60 | Hungary | |
| NCT04738045 | Comparison of Remdesivir Versus Lopinavir/ Ritonavir and Remdesivir Combination in COVID-19 Patients | Recruiting | 90 | Egypt | |
| FVP and RDV | NCT04694612 | Efficacy of Favipiravir in Treatment of Mild & Moderate COVID-19 Infection | Recruiting | 676 | Nepal |
| NCT04784559 | Trial to Determine the Efficacy/Safety of Plitidepsin vs Control in Patients with Moderate COVID-19 Infection (Neptuno) | Recruiting | 609 | Argentina, Brazil | |
| NCT05041907 | Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in (PLATCOV) | Recruiting | 750 | Thailand |
n, estimated enrollment.